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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human plasma vWF protein was used as the immunogen for this von Willebrand Factor antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
WB, Flow, IF, IHC
- 抗体英文名:
von Willebrand Factor / vWF Antibody [F8/86]
- 抗体名:
von Willebrand Factor / vWF Antibody [F8/86]
- 规格:
100ug
von Willebrand Factor / vWF 抗体 [F8/86],von Willebrand Factor / vWF Antibody [F8/86],von Willebrand Factor / vWF 抗体 [F8/86],von Willebrand Factor / vWF Antibody [F8/86]
产品名称:von Willebrand Factor / vWF 抗体 [F8/86]-von Willebrand Factor / vWF Antibody [F8/86]
产品货号:PSI-33-608-100ug
产品规格:100ug
背景资料:von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
保存建议:von Willebrand Factor / vWF 抗体 [F8/86]-von Willebrand Factor / vWF Antibody [F8/86]Aliquot and Store at 2-8℃
应用类型:WB, Flow, IF, IHC
点击:von Willebrand Factor / vWF 抗体 [F8/86]-von Willebrand Factor / vWF Antibody [F8/86]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Multimeric Analysis of von Willebrand Factor
Von Willebrand Factor (vWF) in normal plasma is composed of a series of high molecular multimers, ranging in size from 8�105 to over 15�106 Daltons (1 ). The multimeric structure of vWF was first investigated by two-dimensional crossed
Screening for Candidate Mutations Causing von Willebrands Disease (vWD)
von Willebrand factor (vWF) is a large, complex glycoprotein that exists in plasma and platelets, and is synthesized by megakaryocytes and endothelial cells. vWF plays an essential role in hemostasis in at least two ways. It is involved
., Schroder, W., Zirngibl, H. and Nieswandt, B. (2000). Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies . Blood 95(3): 886-93. Bizzaro, N. and Fiorin, F. (1999
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