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- 文献和实验
- 技术资料
- 免疫原:
Human thymus cells were used as the immunogen for this CD1a antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IHC, IF
- 抗体英文名:
CD1a Antibody [O10]
- 抗体名:
CD1a Antibody [O10]
- 规格:
100ug
CD1a 抗体 [O10],CD1a Antibody [O10],CD1a 抗体 [O10],CD1a Antibody [O10]
产品名称:CD1a 抗体 [O10]-CD1a Antibody [O10]
产品货号:PSI-33-076-100ug
产品规格:100ug
背景资料:At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict Tcell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. CD1a antibody labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibody against TTF-1 and CD5, CD1a antibody is useful in distinguishing between pulmonary and thymic neoplasms since it is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. CD1a antibody is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
保存建议:CD1a 抗体 [O10]-CD1a Antibody [O10]Aliquot and Store at 2-8℃
应用类型:Flow, IHC, IF
点击:CD1a 抗体 [O10]-CD1a Antibody [O10]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验CD1a/CD1b/CD1c/CD1d分子 CD1a 常用单克隆抗体或代号:T6,Leu6 主要表达细胞:Thy,DCsub,LHC,Bsub T细胞 分子质量(kDa)和结构:gp49(IgSF) 功 能:与β2m组成MHCI类样分子,有抗原提呈功能 CD1b 常用单克隆抗体或代号:WM-25,4A7.6,NUT2 主要表达细胞:Thy,DC,LHC,Bsub T细胞 分子
针对传统技术难以解析T细胞发育连续动态的瓶颈,德国汉堡大学团队推出了14色流式方案(OMIP-073)。该方案通过精准圈门与抗体优化,完整描绘了从早期祖细胞到成熟T细胞的14个关键发育阶段,并利用CD1a、CD28等标志物清晰界定了β选择及外迁等核心检查点。流式细胞术作为一套标准化的高分辨率分析工具,它能有效识别健康及疾病状态下的胸腺发育异常,为免疫疾病的机制研究提供了强有力的支持。 Panel方案该14色流式检测方案(OMIP-073)通过组合多种荧光标记抗体,实现了对人类胸腺细胞发育全过程
,dilute your primary antibody in BSA/PBST (15 ml is enough for one blot in a little clear--square--box,use 25 ml for 2 blots).Pour off wash,then immediately add the primary antibody.Incubate at room temp,60 minutes or overnight at 4℃.Pour off.7.Wash 4 X 10
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