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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
The large subunit domain of human Caspase-3 was used as the immunogen for this monoclonal antibody.
- 保存条件:
Aliquot and Store at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
WB
- 抗体英文名:
Caspase-3 (Pro and Active) Antibody [CAS3836]
- 抗体名:
Caspase-3 (Pro and Active) Antibody [CAS3836]
- 规格:
100ug
Caspase-3 (Pro and Active) 抗体 [CAS3836],Caspase-3 (Pro and Active) Antibody [CAS3836],Caspase-3 (Pro and Active) 抗体 [CAS3836],Caspase-3 (Pro and Active) Antibody [CAS3836]
产品名称:Caspase-3 (Pro and Active) 抗体 [CAS3836]-Caspase-3 (Pro and Active) Antibody [CAS3836]
产品货号:PSI-33-007-100ug
产品规格:100ug
背景资料:Caspases, or cysteine-aspartic proteases, are a family of cysteine proteases that play essential roles in inflammation, apoptosis and necrosis. They are often referred to as the 'executioners of apoptosis.' Caspases are synthesized as inactive proenzymes comprising an N-terminal peptide (prodomain) together with one large and one small subunit. Active caspase-1 and -3 are heterodimers, containing two small and two large subunits. Active Caspase-3 subunits are 17kD (p17) and 12kD (p12). Pro Caspase-3 is inactive and has virtually no activity until it is cleaved by an initiator caspase. It is activated by Caspases -8, -9 and -10 ('initiator caspases') and then effects apoptosis by cleaving targeted cellular proteins.
保存建议:Caspase-3 (Pro and Active) 抗体 [CAS3836]-Caspase-3 (Pro and Active) Antibody [CAS3836]Aliquot and Store at -20℃
应用类型:WB
点击:Caspase-3 (Pro and Active) 抗体 [CAS3836]-Caspase-3 (Pro and Active) Antibody [CAS3836]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验of the rhodamine 110, bis-L-aspartic acid amide substrate by active caspase-3. The staining pattern of the Hoechst 33342 dye reveals that the majority of the rhodamine 110–positive cells also contain condensed or fragmented nuclei characteristic of apoptosis
from cleavage of the rhodamine 110, bis-L-aspartic acid amide substrate by active caspase-3. The staining pattern of the Hoechst 33342 dye reveals that the majority of the rhodamine 110�positive cells also contain condensed or fragmented nuclei characteristic
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