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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Ni-NTA purified truncated recombinant P16 expressed in E. Coli strain BL21 (DE3).
- 保存条件:
stored at -20℃, stable for one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
E, WB, IHC
- 抗体英文名:
P16 Antibody [1E12E10]
- 抗体名:
P16 Antibody [1E12E10]
- 规格:
0.1mL
P16 抗体 [1E12E10] ,P16 Antibody [1E12E10] ,P16 抗体 [1E12E10] ,P16 Antibody [1E12E10]
产品名称:P16 抗体 [1E12E10] -P16 Antibody [1E12E10]
产品货号:PSI-32-203-0.1mL
产品规格:0.1mL
背景资料:The progression of cells through the cell cycle is regulated by a family of protein kinases known as cyclin-dependent kinases (Cdks). The sequential activation of individual members of this family and their consequent phosphorylation of critical substrates promotes orderly progression through the cell cycle. The cyclins function as differentially expressed positive regulators of Cdks. Negative regulators of the cycle include the p53-inducible 21 kDa WAF1/Cip1 protein designated p21, Kip1 p27 and p16. The complexes formed by Cdk4 and the D-type cyclins have been strongly implicated in the control of cell proliferation during the G1 phase. It has recently been shown that p16 binds to Cdk4 and inhibits the catalytic activity of the Cdk4/cyclin D complex. Moreover, the gene encoding p16 exhibits a high frequency of homozygous deletions and point mutations in established human tumor cell lines.
保存建议:P16 抗体 [1E12E10] -P16 Antibody [1E12E10] stored at -20℃, stable for one year
应用类型:E, WB, IHC
点击:P16 抗体 [1E12E10] -P16 Antibody [1E12E10] 查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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