MSH2 抗体 [3A2B8C] -MSH2 Antibod

MSH2 抗体 [3A2B8C] ，MSH2 Antibody [3A2B8C] ，MSH2 抗体 [3A2B8C] ,MSH2 Antibody [3A2B8C]

产品名称：MSH2 抗体 [3A2B8C] -MSH2 Antibody [3A2B8C]

产品货号：PSI-32-196-0.1mg

产品规格：0.1mg

背景资料：MSH2 is a 100 kDa nuclear antigen and encodes a protein of 934 amino acids. The MSH2 gene is one of 4 known genes encoding proteins involved in the repair of mismatch nucleotides following DNA replication or repair. Mutations in the MSH2 gene contribute to the development of sporadic colorectal carcinoma. MSHS mutations are responsible for 50% of inherited non-polyposis colorectal (HNPCC). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process.

保存建议：MSH2 抗体 [3A2B8C] -MSH2 Antibody [3A2B8C] stored at -20℃, stable for one year

应用类型：E, WB, IHC

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