E2F1 抗体-E2F1 Antibody

E2F1 抗体，E2F1 Antibody，E2F1 抗体,E2F1 Antibody

产品名称：E2F1 抗体-E2F1 Antibody

产品货号：PSI-16-727-50uL

产品规格：50uL

背景资料：The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

保存建议：E2F1 抗体-E2F1 AntibodyStore at -20℃

应用类型：WB,IF

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