E2F1 抗体 -E2F1 Antibody

E2F1 抗体 ，E2F1 Antibody ，E2F1 抗体 ,E2F1 Antibody

产品名称：E2F1 抗体 -E2F1 Antibody

产品货号：PSI-63-020-400ul

产品规格：400ul

背景资料：E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another two members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

保存建议：E2F1 抗体 -E2F1 Antibody Store at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB

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