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- ProSci
- 美国
- PSI-15-710-50uL
- 2025年07月06日
- WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant fusion protein containing a sequence corresponding to amino acids 696-856 of human ORC1 (NP_001177748.1).
- 保存条件：
Store at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB
- 抗体英文名：
ORC1 Antibody
- 抗体名：
ORC1 Antibody
- 规格：
50uL
ORC1 抗体，ORC1 Antibody，ORC1 抗体,ORC1 Antibody
产品名称：ORC1 抗体-ORC1 Antibody
产品货号：PSI-15-710-50uL
产品规格：50uL
背景资料：The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
保存建议：ORC1 抗体-ORC1 AntibodyStore at -20℃
应用类型：WB
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