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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human Aromatase (NP_000094.2).
- 保存条件:
Store at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB,IHC,IF
- 抗体英文名:
Aromatase Antibody
- 抗体名:
Aromatase Antibody
- 规格:
50uL
Aromatase 抗体,Aromatase Antibody,Aromatase 抗体,Aromatase Antibody
产品名称:Aromatase 抗体-Aromatase Antibody
产品货号:PSI-14-578-50uL
产品规格:50uL
背景资料:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
保存建议:Aromatase 抗体-Aromatase AntibodyStore at -20℃
应用类型:WB,IHC,IF
点击:Aromatase 抗体-Aromatase Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验存在于胎盘、马睾丸等微粒体部分,使△4 -3- 氧甾醇的 A 环芳构化,变成酚型酶。开始是 19 位的甲基由 19- 羟化酶进行二次羟化成为二羟化物,接着脱水形成 19- 氧代化物,然后,在 10 位与 19 位之间切断的同时失去 1 位与 2 位的氢而成为醌,烯醇化后生成酚。因此,此系统由 19- 羟化酶与 C 10 -C 19 裂解酶构成,均需要分子态氧与 NADPH 。
Efficient Expression of Human Aromatase (CYP19) in E. coli
Human aromatase (CYP19, P450arom) is responsible for the conversion of androgens to estrogens. In addition to the estrogen biosynthesis in gonads and adrenals in a classical endocrine manner, this enzyme is widely expressed in various tissues
在免疫反应方面,基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体,按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等,但这些并不等于有相应的不同抗体存在,一般多只表明抗体反应的多样性而已。抗体在血清中含量最多(体液抗体=humoral antibody);含有某特定抗体的血清称为抗血或免疫血清。
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