STAT3 抗体 [A2G8]-STAT3 Antibody

STAT3 抗体 [A2G8]，STAT3 Antibody [A2G8]，STAT3 抗体 [A2G8],STAT3 Antibody [A2G8]

产品名称：STAT3 抗体 [A2G8]-STAT3 Antibody [A2G8]

产品货号：PSI-13-949-50uL

产品规格：50uL

背景资料：The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

保存建议：STAT3 抗体 [A2G8]-STAT3 Antibody [A2G8]Store at -20℃

应用类型：WB,IHC,IF

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