UVRAG 抗体-UVRAG Antibody

UVRAG 抗体，UVRAG Antibody，UVRAG 抗体,UVRAG Antibody

产品名称：UVRAG 抗体-UVRAG Antibody

产品货号：PSI-7947-0.02mg

产品规格：0.02mg

背景资料：The class III type phosphoinositide 3-kinase (PI3KC3) / Vps34 regulates vacuolar trafficking as well as autophagy (1). UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (2). UVRAG is highly expressed in brain, lung, kidney and liver and contains one C2 domain, which is involved in calcium-dependent phospholipid binding. Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (3). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (4,5).

保存建议：UVRAG 抗体-UVRAG Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P, IF

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