TRIM21 抗体-TRIM21 Antibody

TRIM21 抗体，TRIM21 Antibody，TRIM21 抗体,TRIM21 Antibody

产品名称：TRIM21 抗体-TRIM21 Antibody

产品货号：PSI-7729-0.02mg

产品规格：0.02mg

背景资料：TRIM21, a member of the tripartite motif (TRIM) family, is a part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus (1). RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus (2). TRIM21 also acts as a cytosolic antibody receptor; detection of intracellular antibodies activate immune signaling by stimulating the transcription factor pathways of NF-kappaB, AP-1, IRF3, IRF5, and IRF7, resulting in the production of proinflammatory cytokines and the induction of an antiviral state (3).

保存建议：TRIM21 抗体-TRIM21 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P, IF

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