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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
TERF2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TERF2.<br>The immunogen is located within the first 50 amino acids of TERF2.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IHC-P
- 抗体英文名:
TERF2 Antibody
- 抗体名:
TERF2 Antibody
- 规格:
0.02mg
TERF2 抗体,TERF2 Antibody,TERF2 抗体,TERF2 Antibody
产品名称:TERF2 抗体-TERF2 Antibody
产品货号:PSI-7727-0.02mg
产品规格:0.02mg
背景资料:The telomeric repeat binding factor family (TERF1 and TERF2) plays a key role in cellular immortalization and cellular senescence (1). TERF2, as a component of the telomere nucleoprotein complex, is present at telomeres in metaphase of the cell cycle (2). TERF2 is a second negative regulator of telomere length and binds as a dimer to TTAGGG repeats at ends of chromosomes (telomeres), where it blocks inappropriate activation of the ATM/p53 pathway (2,3). TERF1 negatively regulates telomere elongation, while TERF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression (4,5).
保存建议:TERF2 抗体-TERF2 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IHC-P
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