DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE.<br>The immunogen is located within the first 50 amino acids of DELE.
保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
背景资料:DELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
保存建议:DELE 抗体-DELE Antibody stored at 4℃ for three months and -20℃, stable for up to one year