FLT3 antibody was raised against an 18 amino acid synthetic peptide near the center of human FLT3.<br>The immunogen is located within amino acids 340 - 390 of FLT3.
保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
背景资料:FLT3 Antibody: FLT3 is a member of the class III receptor tyrosine kinase family and its internal tandem duplication (ITD) is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. It is a membrane bound glycosylated protein that is expressed primarily in early hematopoietic progenitor cells. Upon binding its ligand FL, FLT3 activates multiple signaling pathways including the PI3K/Akt and Ras/MEK/MAPK pathways. In cells expressing FLT3-ITD, these pathways are constitutively on, resulting in abnormal cell growth and anti-apoptotic activity.
保存建议:FLT3 抗体-FLT3 Antibody stored at 4℃ for three months and -20℃, stable for up to one year