SPG15 抗体-SPG15 Antibody

SPG15 抗体，SPG15 Antibody，SPG15 抗体,SPG15 Antibody

产品名称：SPG15 抗体-SPG15 Antibody

产品货号：PSI-5023-0.02mg

产品规格：0.02mg

背景资料：SPG15 Antibody: Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.  Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration. SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. SPG15 mRNA is widely distributed in human tissues, as well as in rat embryos, suggesting a possible role for this protein during embryonic development. SPG15 co-localizes partially with endoplasmic reticulum and endosome markers, suggesting a role in intracellular trafficking.

保存建议：SPG15 抗体-SPG15 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IF

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