Slc35D1 抗体-Slc35D1 Antibody

Slc35D1 抗体，Slc35D1 Antibody，Slc35D1 抗体,Slc35D1 Antibody

产品名称：Slc35D1 抗体-Slc35D1 Antibody

产品货号：PSI-4607-0.02mg

产品规格：0.02mg

背景资料：Slc35D1 Antibody: The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.

保存建议：Slc35D1 抗体-Slc35D1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, ICC

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