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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
RTP801 antibody was raised against a 12 amino acid synthetic peptide from near the center of human RTP801.<br>The immunogen is located within amino acids 90 - 140 of RTP801.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IHC-P, IF
- 抗体英文名:
RTP801 Antibody
- 抗体名:
RTP801 Antibody
- 规格:
0.02mg
RTP801 抗体,RTP801 Antibody,RTP801 抗体,RTP801 Antibody
产品名称:RTP801 抗体-RTP801 Antibody
产品货号:PSI-4495-0.02mg
产品规格:0.02mg
背景资料:RTP801 Antibody: RTP801 was initially identified as a gene induced by DNA damage, and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment. Recently, RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle. In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. Disregulation of RTP801 may thus contribute to human tumorigenesis.
保存建议:RTP801 抗体-RTP801 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IHC-P, IF
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文献和实验Phycoerythrin conjugation protocol
Phycoerythrin conjugation protocol David's method modified from references (2) and (3). I used this method to conjugate a mouse IgG2a monoclonal antibody (IB4). It works well. Reagents Ab Antibody
-1Ra 后,关节穿刺液中 IL-1Ra 浓度随时间的变化。 疼痛和功能改善:患者报告的疼痛和功能评分在研究期间有所改善。低剂量组患者的疼痛改善较为显著,中高剂量 组患者的改善更为持久。 免疫反应:大多数患者在基线时存在低水平的 AAV2.5 中和抗体(NAbs),注射后中和抗体滴度有所上升,但未检测 到细胞介导的免疫反应。 应用案例 2:异位骨化的抑制[4] 背景知识:FOP(Fibrodysplasia Ossificans Progressiva, FOP)是一种由 ACVR1 基因突变引起的遗传
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