Bid antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bid.<br>The immunogen is located within amino acids 120 - 170 of Bid.
保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
背景资料:Bid Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals, exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein. The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize.
保存建议:Bid 抗体-Bid Antibody stored at 4℃ for three months and -20℃, stable for up to one year