- ￥22
- ProSci
- 美国
- PSI-3269-0.02mg
- 2025年07月07日
- E, WB, ICC
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the center of mouse TLR7.<br>The immunogen is located within amino acids 420 - 470 of TLR7.
- 保存条件：
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB, ICC
- 抗体英文名：
TLR7 Antibody
- 抗体名：
TLR7 Antibody
- 规格：
0.02mg
TLR7 抗体，TLR7 Antibody，TLR7 抗体,TLR7 Antibody
产品名称：TLR7 抗体-TLR7 Antibody
产品货号：PSI-3269-0.02mg
产品规格：0.02mg
背景资料：TLR7 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.
保存建议：TLR7 抗体-TLR7 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型：E, WB, ICC
点击：TLR7 抗体-TLR7 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Development of TLR7/8 Small RNA Antagonists
Toll-like receptors (TLRs) expressed by innate immune cells recognize a spectrum of microbial structures. Recent studies have provided convincing evidence that TLR7 and TLR8 play a key role in sensing viral RNAs. Under certain conditions
Viral single-stranded (ss) RNA is the natural ligand for TLR7 and TLR8. Synthetic ssRNA has been shown to act as a ligand for TLR7 and TLR8. We have previously reported a novel RNA structure, referred to as stabilized immune modulatory RNA
在免疫反应方面，基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体，按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等，但这些并不等于有相应的不同抗体存在，一般多只表明抗体反应的多样性而已。抗体在血清中含量最多（体液抗体=humoral antibody）；含有某特定抗体的血清称为抗血或免疫血清。
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