- ￥2262
- LSM Bio
- 进口
- PAab08730
- 2025年07月12日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
toll-like receptor 7
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
toll-like receptor 7
- 抗体英文名：
anti-TLR7 antibody,TLR7 antibody
- 抗体名：
anti-TLR7 抗体,TLR7 抗体
- 规格：
100μg
TLR7抗体| TLR7 antibody
货号 PAab08730
蛋白别名
蛋白介绍
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
产品描述
anti-TLR7 antibody is a Rabbit Polyclonal antibody againstTLR7..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using PAab08730( TLR7 Antibody) at dilution of 1:50
Western blot
mouse lung tissue were subjected to SDS PAGE followed by western blot with PAab08730(TLR7 antibody) at dilution of 1:400(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验Development of TLR7/8 Small RNA Antagonists
Toll-like receptors (TLRs) expressed by innate immune cells recognize a spectrum of microbial structures. Recent studies have provided convincing evidence that TLR7 and TLR8 play a key role in sensing viral RNAs. Under certain conditions
Viral single-stranded (ss) RNA is the natural ligand for TLR7 and TLR8. Synthetic ssRNA has been shown to act as a ligand for TLR7 and TLR8. We have previously reported a novel RNA structure, referred to as stabilized immune modulatory RNA
Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells
-like receptor 7 (TLR7) in the activation of the corresponding autoantibody producing B cells. Importantly, TLR9/TLR7-deficiency results in the inability of autoreactive B cells to proliferate in response to DNA/RNA-associated autoantigens in vitro, and in marked
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