IL-13 Protein, Cynomolgus, Recombinant

IL-13 Protein, Cynomolgus, Rec

ombinant
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  • $15000
  • Leading Biology
  • 美国
  • PK54218M0
  • 2025年07月16日
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    • 详细信息
    • 技术资料
    • 保存条件

      Stable for 1 year at -4238°C or below from date of shipment.

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 规格

      1 mg

    蛋白长度:A DNA sequence encoding the Cynomolgus (Macaca fascicularis) IL13 (ABG75889.1) (Met 1-Asn 132) precursor was expressed.

    性质:

    表达系统:HEK293 Cells

    种属:Cynomolgus

    氨基酸序:Met1-Asn132

    标签类型:No tag

    分子量:The recombinant Cynomolgus IL13 consists of 112 amino acids and has a calculated molecular mass of 12.3 kDa as estimated by SDS-PAGE under reducing conditions.

    活性:Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.The EDfor this effect is typically 2-8 ng/mL.

    内毒素:< 1.0 EU per μg of the protein as determined by the LAL method.

    基因名称:interleukin 13

    通用名:IL13

    蛋白序参考:ABG75889.1

    总结:Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

    形式:Lyophilized

    纯度:> 85 % as determined by SDS-PAGE.

    储存条件:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

    储存溶液:Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

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