CD38 Protein, Mouse, Recombina

蛋白长度：A DNA sequence encoding the extracellular domain of mouse CD38 (NP_031672.2) (Leu 45-Thr 304) was expressed, fused with a C-terminal polyhistidine tag.

性质：

表达系统：HEK293 Cells

种属：Mouse

氨基酸序：Leu45-Thr304

标签类型：C-His

分子量：The recombinant mouse CD38 consists of 271 amino acids and has a calculated molecular mass of 31.3 kDa. As a result of glycosylation, the apparent molecular mass of rmCD38 is approximately 38-42 kDa in SDS-PAGE under reducing conditions.

活性：Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDPribose. The specific activity is >50,000pmols/min/ug.

内毒素：< 1.0 EU per μg of the protein as determined by the LAL method.

基因名称：CD38 molecule

通用名：CD38

蛋白序参考：NP_031672.2

总结：The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4, CD8, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NADto ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

形式：Lyophilized

纯度：> 97 % as determined by SDS-PAGE.

储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

储存溶液：Lyophilized from sterile 20mM MES, 0.15M NaCl, pH 6.5 Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

别名：ADPRC 1-rs1 Protein, Mouse; ADPRC1 Protein, Mouse; Cd38 Protein, Mouse; Cd38-rs1 Protein, Mouse; I-19 Protein, Mouse