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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD80
- 级别:
CD80 Antibody
- 目录编号:
CD80 Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD80 Antibody
- 抗体英文名:
Dazzle™ 594 anti-human CD80 Antibody-PE
- 抗体名:
CD80 Antibody
- 标记物:
PE
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD80 Antibody
- 亚型:
CD80 Antibody
- 形态:
CD80 Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
CD80 Antibody
- 规格:
25 tests/100 tests
| 规格: | 25 tests | 产品价格: | ¥2400.0 |
|---|---|---|---|
| 规格: | 100 tests | 产品价格: | ¥5500.0 |
Description :CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belongingto the immunoglobulin superfamily. CD80 is expressed on activated B and T cells,macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along withCD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 withCD28 provides a potent costimulatory signal for T cell activation through the CD3 complex,while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
Verified Reactivity :Human
Reported Reactivity :Rhesus
Antibody Type :Monoclonal
Host Species :Mouse
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 underoptimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
Excitation Laser :Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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文献和实验1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
2. Battifora M. 1998. J. Clin. Endocr. Metab. 83:4130. (IHC)
3. Van der Merwe PA, et al. 1997. J. Exp. Med. 185:3. (WB)
4. Jayakumar A, et al. 2008. Infect. Immun. 76:2138. PubMed
5. Schubert DA, et al. 2012. J. Exp Med. 209:335. PubMed
6. Wen T, et al. 2014. J Immunol. 192:5481. PubMed
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