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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD61
- 级别:
CD61 Antibody
- 目录编号:
CD61 Antibody
- 克隆性:
单克隆
- 抗原来源:
亚美尼亚仓鼠
- 保质期:
CD61 Antibody
- 抗体英文名:
anti-mouse/rat CD61 Antibody-APC
- 抗体名:
CD61 Antibody
- 标记物:
APC
- 宿主:
亚美尼亚仓鼠
- 适应物种:
小鼠、大鼠
- 免疫原:
CD61 Antibody
- 亚型:
CD61 Antibody
- 形态:
CD61 Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
0.2 mg/ml
- 规格:
25 µg/100 µg
| 规格: | 25 µg | 产品价格: | ¥1700.0 |
|---|---|---|---|
| 规格: | 100 µg | 产品价格: | ¥3900.0 |
anti-mouse/rat CD61 Antibody-APC详细如下:
Description :CD61 is a 110 kD integrin β chain also known as β integrin or gpIIIa. It associates with theintegrin α chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate withthe integrin α chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets,megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts,and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin,fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelialadhesion is mediated by the binding of α /β integrin or vitronectin receptor to CD31 (PECAM1).
Verified Reactivity :Mouse, Rat
Antibody Type :Monoclonal
Host Species :Armenian Hamster
Immunogen :Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.
Concentration :0.2 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser :Red Laser (633 nm)
Description :CD61 is a 110 kD integrin β chain also known as β integrin or gpIIIa. It associates with theintegrin α chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate withthe integrin α chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets,megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts,and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin,fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelialadhesion is mediated by the binding of α /β integrin or vitronectin receptor to CD31 (PECAM1).
Verified Reactivity :Mouse, Rat
Antibody Type :Monoclonal
Host Species :Armenian Hamster
Immunogen :Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.
Concentration :0.2 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser :Red Laser (633 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Kieffer N, et al. 1990. Annu. Rev. Cell Biol. 6:329. (Block)
2. Piali L, et al. 1995. J. Cell Biol. 130:451. (Block)
3. Ashkar S, et al. 2000. Science 287:860. (Block)
4. Schultz JF, et al. 1995. J. Biol. Chem. 270:11522. (Block)
5. Moulder K, et al. 1991. J. Exp. Med. 173:343. (Activ)
6. Carlson TR, et al. 2008.135:2193. PubMed
7. Yamaji D, et al. 2009. Genes Dev. 23:2382. PubMed
Product Citations:
1. Dignum T, et al. 2021. Cell Rep. 36:109675. PubMed
2. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
3. Flommersfeld S, et al. 2021. Immunity. :. PubMed
4. Yamamoto M, et al. 2019. Commun Biol. 2:292. PubMed
5. Pervolarakis N, et al. 2020. Cell Rep. 108273:33. PubMed
6. Ni T, et al. 2016. Nat Cell Biol. 18:1221-1232. PubMed
7. Lucotti S, et al. 2019. J Clin Invest. 130:1845. PubMed
1. Kieffer N, et al. 1990. Annu. Rev. Cell Biol. 6:329. (Block)
2. Piali L, et al. 1995. J. Cell Biol. 130:451. (Block)
3. Ashkar S, et al. 2000. Science 287:860. (Block)
4. Schultz JF, et al. 1995. J. Biol. Chem. 270:11522. (Block)
5. Moulder K, et al. 1991. J. Exp. Med. 173:343. (Activ)
6. Carlson TR, et al. 2008.135:2193. PubMed
7. Yamaji D, et al. 2009. Genes Dev. 23:2382. PubMed
Product Citations:
1. Dignum T, et al. 2021. Cell Rep. 36:109675. PubMed
2. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
3. Flommersfeld S, et al. 2021. Immunity. :. PubMed
4. Yamamoto M, et al. 2019. Commun Biol. 2:292. PubMed
5. Pervolarakis N, et al. 2020. Cell Rep. 108273:33. PubMed
6. Ni T, et al. 2016. Nat Cell Biol. 18:1221-1232. PubMed
7. Lucotti S, et al. 2019. J Clin Invest. 130:1845. PubMed
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