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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from Human Raf-B around the non-phosphorylation site of S602.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
多克隆
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
12个月
- 抗原来源:
Human
- 目录编号:
CSB-PA003928
- 级别:
多克隆抗体
- 库存:
充足
- 供应商:
武汉益普生物科技有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, WB, IHC
- 靶点:
BRAF
- 抗体英文名:
BRAF Antibody
- 规格:
50μg/100μg
| 规格: | 50μg | 产品价格: | ¥1090.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | ¥1590.0 |
| 产品名称 | BRAF Antibody |
| 货号 | CSB-PA003928 |
| 别名 | FLJ95109 antibody; 94 kDa B raf protein antibody; B raf 1 antibody; B raf antibody; B Raf proto oncogene serine threonine protein kinase antibody; B Raf proto oncogene; serine/threonine kinase antibody; B RAF1 antibody; B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody; BRAF 1 antibody; BRAF antibody; BRAF_HUMAN antibody; BRAF1 antibody; cRmil antibody; MGC126806 antibody; MGC138284 antibody; Murine sarcoma viral (v-raf) oncogene homolog B1 antibody; Murine sarcoma viral v raf oncogene homolog B1 antibody; NS7 antibody; Oncogen BRAF antibody; oncogene BRAF1 antibody; p94 antibody; Proto-oncogene B-Raf antibody; Proto-oncogene c-Rmil antibody; RAFB 1 antibody; RAFB1 antibody; RMIL antibody; Serine/threonine-protein kinase B-raf antibody; v raf murine sarcoma viral oncogene homolog B antibody; v raf murine sarcoma viral oncogene homolog B1 antibody; v-Raf murine sarcoma viral oncogene homolog B1 antibody |
| 抗体类型 | Polyclonal Antibody |
| 克隆类型 | Polyclonal |
| Uniprot No. | P15056 |
| 基因名 | BRAF |
| 免疫原种属 | Human |
| 免疫原 | Synthesized peptide derived from Human Raf-B around the non-phosphorylation site of S602. |
| 宿主 | Rabbit |
| 反应种属 | Human, Mouse, Rat |
| 应用范围 | ELISA, WB, IHC |
| 抗体亚型 | IgG |
| 标记方式 | Non-conjugated |
| 产品提供形式 | Liquid |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 研究领域 | Cell Biology |
| 保存缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 储存条件 | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |

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文献和实验或可疑恶性患者的术后病理发现,仅20%~25%为甲状腺癌,而另75%~80%的患者则接受了不必要的甲状腺手术[3]。因此,如何正确处理这些FNAB无法确诊的病例,是目前面临的最大困难和挑战。 BRAF V600E是一个突出的PTC癌基因,占BRAF基因突变的80%,BRAF基因突变对PTC具有较好的特异性,BRAF突变阳性,几乎就可以确诊为PTC。因此,BRAF V600E对于乳头状甲状腺瘤来说是一种重要的诊断标记物,可以指导医师为细胞学诊断不能确诊的患者选择最佳的治疗方案。 表
Detecting Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma
V600 BRAF mutation was identified as an ideal target for clinical therapy due to its indispensable roles in supporting melanoma initiation and progression. Despite the fact that BRAF inhibitors (BRAFi) can elicit anti-tumor responses
Assaying for BRAF V600E in Tissue and Blood in Melanoma
The BrafV600E mutation has been detected in patients with metastatic melanoma, colon, thyroid, and other cancers. Studies suggested that tumors with this mutation are especially sensitive to BRAF inhibitors-hence the need to reliably
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