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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD154
- 级别:
CD154 Antibody
- 目录编号:
CD154 Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD154 Antibody
- 抗体英文名:
anti-human CD154 Antibody-FITC
- 抗体名:
CD154 Antibody
- 标记物:
FITC
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD154 Antibody
- 亚型:
CD154 Antibody
- 形态:
CD154 Antibody
- 应用范围:
FC, IHC-F
- 保存条件:
2-8℃
- 浓度:
CD154 Antibody
- 规格:
100 tests
anti-human CD154 Antibody-FITC详细如下:
Description :CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and isexpressed on activated T cells. It has been reported to be important for B cell costimulationfollowing binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cellspromotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved inthe regulation of cytokine production by T cells.
Verified Reactivity :Human
Reported Reactivity :Cynomolgus, Rhesus
Antibody Type :Monoclonal
Host Species :Mouse
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration :Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentrationand Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser :Blue Laser (488 nm)
Description :CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and isexpressed on activated T cells. It has been reported to be important for B cell costimulationfollowing binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cellspromotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved inthe regulation of cytokine production by T cells.
Verified Reactivity :Human
Reported Reactivity :Cynomolgus, Rhesus
Antibody Type :Monoclonal
Host Species :Mouse
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration :Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentrationand Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser :Blue Laser (488 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Brams P, et al. 2001. Int. Immunopharmacol. 1:277. (Block, IF)
2. Rushworth SA, et al. 2002. Transplantation 73:635. (Block)
3. Berner B, et al. 2000. Ann. Rheum. Dis. 59:190. (IF)
4. Nordström T, et al. 2006. J. Leukocyte Biol. 79:319. (Block)
5. Zhang AL, et al.2007. Blood doi:10.1182/blood-2007-02-076364. (Block) PubMed
6. Kuchen S, et al. 2007. J. Immunol. 179:5886.
7. Matus-Nicodermos R, et al. 2011. J. Immunol. 186:2164. PubMed
8. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
Product Citations:
1. Hristov M, et al. 2010. Circulation. 121:315. PubMed
2. Lamichhane R, et al. 2020. Eur J Immunol. 50:178. PubMed
3. Carnevale J, et al. 2022. Nature. 609:174. PubMed
4. Lindner S, et al. 2013. Cancer Res. 73:2468. PubMed
5. Högelin KA, et al. 2021. iScience. 24:103078. PubMed
6. Lamichhane R et al. 2019. Cell Rep. 28(12):3061-3076 . PubMed
7. Ashar H,et al. 2017. Am J Pathol.. 10.1016/j.ajpath.2017.09.014. PubMed
1. Brams P, et al. 2001. Int. Immunopharmacol. 1:277. (Block, IF)
2. Rushworth SA, et al. 2002. Transplantation 73:635. (Block)
3. Berner B, et al. 2000. Ann. Rheum. Dis. 59:190. (IF)
4. Nordström T, et al. 2006. J. Leukocyte Biol. 79:319. (Block)
5. Zhang AL, et al.2007. Blood doi:10.1182/blood-2007-02-076364. (Block) PubMed
6. Kuchen S, et al. 2007. J. Immunol. 179:5886.
7. Matus-Nicodermos R, et al. 2011. J. Immunol. 186:2164. PubMed
8. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
Product Citations:
1. Hristov M, et al. 2010. Circulation. 121:315. PubMed
2. Lamichhane R, et al. 2020. Eur J Immunol. 50:178. PubMed
3. Carnevale J, et al. 2022. Nature. 609:174. PubMed
4. Lindner S, et al. 2013. Cancer Res. 73:2468. PubMed
5. Högelin KA, et al. 2021. iScience. 24:103078. PubMed
6. Lamichhane R et al. 2019. Cell Rep. 28(12):3061-3076 . PubMed
7. Ashar H,et al. 2017. Am J Pathol.. 10.1016/j.ajpath.2017.09.014. PubMed
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抗人 CD154 荧光标记FITC 抗体
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