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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
Galectin-9
- 级别:
anti-mouse Galectin-9 Antibody
- 目录编号:
anti-mouse Galectin-9 Antibody
- 克隆性:
单克隆
- 抗原来源:
大鼠
- 保质期:
anti-mouse Galectin-9 Antibody
- 抗体英文名:
anti-mouse Galectin-9 Antibody-PE
- 抗体名:
Galectin-9 抗体
- 标记物:
PE
- 宿主:
大鼠
- 适应物种:
小鼠
- 免疫原:
anti-mouse Galectin-9 Antibody
- 亚型:
anti-mouse Galectin-9 Antibody
- 形态:
anti-mouse Galectin-9 Antibody
- 应用范围:
FC, ICFC
- 保存条件:
2-8℃
- 浓度:
0.2 mg/ml
- 规格:
50 ug/200 ug
| 规格: | 50 ug | 产品价格: | ¥2400.0 |
|---|---|---|---|
| 规格: | 200 ug | 产品价格: | ¥5900.0 |
Description :Galectin-9 is a mammalian lectin with a molecular weight of 40 kD that has two conservedcarbohydrate recognition domains (CRDs) and forms homodimers. It recognizes Nacetyllactosamine (Galbeta1-4GlcNAc) and T-antigen (Galbeta1-3GalNAc); Tim-3 has beenreported as its ligand. Galectin-9 is expressed by lymphocytes, dendritic cells, granulocytes,eosinophils, astrocytes, endothelial cells, fibroblasts and thymus epithelial cells. It may beretained intracellularly or be transported to the cell surface where it is cleaved, therebygenerating a soluble form. Galectin-9 is involved in events such as cell aggregation, celladhesion, chemotaxis and apoptosis. Importantly for the regulation of the immune response,Galectin-9 induces regulatory T cells and suppresses Th1 and Th17 responses.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Full length recombinant mouse Galectin-9 (M-type)
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography and conjugated with PE under optimalconditions.
Concentration :0.2 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser :Blue Laser (488 nm)
Green Laser (532 nm)
Yellow-Green Laser (561 nm)
Application Notes :Clone 108A2 recognizes the linker peptide of mouse Galectin-9; it does not cross-react with stableGalectin-9 (which is biologically active, genetically engineered, linker-less Galectin-9) . Additionalreported applications (for the relevant formats) include: sandwich ELISA as capture antibody andimmunohistochemical staining of paraffin embedded tissue sections.
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文献和实验1. Tsuboi Y, et al. 2007. Clin. Immunol. 124:221. (ELISA)
2. Personal communication. (IHC-Paraffin)
3. Oomizu S, et al. 2012. PLoS One. 7:e48574. PubMed
4. Madireddi S, et al. 2014. J Exp Med. 211:1433. PubMed
Product Citations:
1. Madireddi S, et al. 2014. J Exp Med. 211:1433. PubMed
2. Shan M et al. 2018. Immunity. 49(4):709-724 . PubMed
3. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
4. Cao A, et al. 2018. Nat Commun. 9:3288. PubMed
5. Smith LK, et al. 2021. Elife. 10:. PubMed
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