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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD88 (C5aR)
- 级别：
CD88 (C5aR) Antibody
- 目录编号：
CD88 (C5aR) Antibody
- 克隆性：
单克隆
- 抗原来源：
大鼠
- 保质期：
CD88 (C5aR) Antibody
- 抗体英文名：
Cyanine5.5 anti-mouse CD88 (C5aR) Antibody/PerCP
- 抗体名：
CD88 (C5aR) Antibody
- 标记物：
PerCP
- 宿主：
大鼠
- 适应物种：
小鼠
- 免疫原：
CD88 (C5aR) Antibody
- 亚型：
CD88 (C5aR) Antibody
- 形态：
CD88 (C5aR) Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.2 mg/ml
- 规格：
25 ug/100 ug
| 规格： | 25 ug | 产品价格： | ￥2600.0 |
|---|---|---|---|
| 规格： | 100 ug | 产品价格： | ￥6000.0 |
Cyanine5.5 anti-mouse CD88 (C5aR) Antibody/PerCP详细如下：
Description ：CD88 is a single chain protein with seven membrane-spanning regions and a molecular weightof 43 kD. CD88 is expressed by neutrophils, eosinophils, and monocytes. There have beenreports of CD88 expression in non-immune cells such as glial cells, cerebellar granule cells,cardiomyocytes, and vascular endothelial cells. CD88 is coupled to heterotrimeric G proteinssuch as G, and after C5a binding, the signal transduced by CD88 results in the activation ofPLCβ, PI-3 kinase, and PLA , among other molecules, resulting in chemotaxis, granule enzymerelease, and superoxide anion production.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：mC5aR transfected cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5under optimal conditions.
Concentration ：0.2 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is =0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
Excitation Laser ：Blue Laser (488 nm)
Description ：CD88 is a single chain protein with seven membrane-spanning regions and a molecular weightof 43 kD. CD88 is expressed by neutrophils, eosinophils, and monocytes. There have beenreports of CD88 expression in non-immune cells such as glial cells, cerebellar granule cells,cardiomyocytes, and vascular endothelial cells. CD88 is coupled to heterotrimeric G proteinssuch as G, and after C5a binding, the signal transduced by CD88 results in the activation ofPLCβ, PI-3 kinase, and PLA , among other molecules, resulting in chemotaxis, granule enzymerelease, and superoxide anion production.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：mC5aR transfected cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5under optimal conditions.
Concentration ：0.2 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is =0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
Excitation Laser ：Blue Laser (488 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Godau J, et al. 2004. J. Immunol. 173:3437.
2. Shushakova N, et al. 2002. J. Clin. Invest. 110:1823.
3. Kim SH, et al. 2013. Int Immunol. 25:623. PubMed
Product Citations：
1. Neupane AS, et al. 2020. Cell. 183(1):110-125.e11. PubMed
2. Bosteels C, et al. 2020. Immunity. 52(6):1039-1056.e9.. PubMed
1. Godau J, et al. 2004. J. Immunol. 173:3437.
2. Shushakova N, et al. 2002. J. Clin. Invest. 110:1823.
3. Kim SH, et al. 2013. Int Immunol. 25:623. PubMed
Product Citations：
1. Neupane AS, et al. 2020. Cell. 183(1):110-125.e11. PubMed
2. Bosteels C, et al. 2020. Immunity. 52(6):1039-1056.e9.. PubMed
文献支持
Cyanine5.5 抗小鼠 CD88 (C5aR) 抗体/PerCP
￥2600 - 6000
