Cyanine7 抗小鼠 TIGIT (Vstm3) 荧光标

Cyanine7 anti-mouse TIGIT (Vstm3) Antibody-PE详细如下：

Description ：T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as V-set andtransmembrane domain-containing protein 3 (Vstm3), is a 26 kD, type I transmembrane proteinand member of the CD28 family. TIGIT is expressed on activated T cells, follicular T helper,memory, and regulatory T cells as well as on NK cells. Its binding partners include CD155(PVR) and CD112 (PVRL2). TIGIT is a negative regulator of NK and T cell activation.Engagement of TIGIT by dendritic cells results in their differentiation into a tolerogenicphenotype, with an increased secretion of IL-10 and a diminished production of IL-12. Micedeficient for TIGIT are more susceptible to autoimmune disease.

Verified Reactivity ：Mouse

Antibody Type ：Monoclonal

Host Species ：Mouse

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.

Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)