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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
P2X7R
- 级别：
P2X7R Antibody
- 目录编号：
P2X7R Antibody
- 克隆性：
单克隆
- 抗原来源：
大鼠
- 保质期：
P2X7R Antibody
- 抗体英文名：
anti-mouse P2X7R Antibody-APC
- 抗体名：
P2X7R Antibody
- 标记物：
APC
- 宿主：
大鼠
- 适应物种：
小鼠
- 免疫原：
P2X7R Antibody
- 亚型：
P2X7R Antibody
- 形态：
P2X7R Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.2 mg/ml
- 规格：
25 ug/100 ug
| 规格： | 25 ug | 产品价格： | ￥2600.0 |
|---|---|---|---|
| 规格： | 100 ug | 产品价格： | ￥5600.0 |
anti-mouse P2X7R Antibody-APC详细如下：
Description ：P2X7R, also known as P2X7 receptor, belongs to the family of ligand-gated ion channelreceptors. It is expressed on T cells, B cells, macrophages, and microglia. The receptor opensin the presence of extracellular ATP or NAD, leading to intracellular calcium mobilization.P2X7R activation requires higher concentrations of ATP compared to other P2X receptors.Longer stimulation results in larger pores, allowing passage of larger molecules. Activation ofthese molecules also leads to mitochondrial and cytoskeletal changes as well as IL-1βmaturation and release. Ligation of P2X7 receptor can lead to membrane blebbing and celldeath.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：Murine colon mast cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.
Concentration ：0.2 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser ：Red Laser (633 nm)
Description ：P2X7R, also known as P2X7 receptor, belongs to the family of ligand-gated ion channelreceptors. It is expressed on T cells, B cells, macrophages, and microglia. The receptor opensin the presence of extracellular ATP or NAD, leading to intracellular calcium mobilization.P2X7R activation requires higher concentrations of ATP compared to other P2X receptors.Longer stimulation results in larger pores, allowing passage of larger molecules. Activation ofthese molecules also leads to mitochondrial and cytoskeletal changes as well as IL-1βmaturation and release. Ligation of P2X7 receptor can lead to membrane blebbing and celldeath.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：Murine colon mast cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.
Concentration ：0.2 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser ：Red Laser (633 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Kurashima Y, et al. 2012. Nat. Commun. 3:1034. (FC, IP, WB, IHC, FA)
Product Citations：
1. Zhou Y, et al. 2020. Immunity. 52(2):357-373. PubMed
2. Hiltensperger M, et al. 2021. Nat Immunol. 22:880. PubMed
3. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
4. Borges da Silva H, et al. 2020. Immunity. 53(1):158-171.e6. PubMed
1. Kurashima Y, et al. 2012. Nat. Commun. 3:1034. (FC, IP, WB, IHC, FA)
Product Citations：
1. Zhou Y, et al. 2020. Immunity. 52(2):357-373. PubMed
2. Hiltensperger M, et al. 2021. Nat Immunol. 22:880. PubMed
3. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
4. Borges da Silva H, et al. 2020. Immunity. 53(1):158-171.e6. PubMed
文献支持
抗小鼠 P2X7R 荧光标记APC 抗体
￥2600 - 5600
