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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
TSLPR (TSLP-R)
- 级别：
TSLPR (TSLP-R) Antibody
- 目录编号：
TSLPR (TSLP-R) Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
TSLPR (TSLP-R) Antibody
- 抗体英文名：
anti-human TSLPR (TSLP-R) Antibody-PE
- 抗体名：
TSLPR (TSLP-R) Antibody
- 标记物：
PE
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
TSLPR (TSLP-R) Antibody
- 亚型：
TSLPR (TSLP-R) Antibody
- 形态：
TSLPR (TSLP-R) Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
TSLPR (TSLP-R) Antibody
- 规格：
100 tests
anti-human TSLPR (TSLP-R) Antibody-PE详细如下：
Description ：TSLP-R, also known as thymic stromal lymphopoietin protein receptor, cytokine receptor-like 2,CRL2, and IL-XR, is a type I membrane receptor that forms a functional heterodimeric complexwith IL-7R to bind TSLP. The TSLP-R contains a WSXWS motif required for proper proteinfolding and a box1 motif important for association with the JAKs. TSLP-R has a predictedmolecular weight approximately 40 kD, and two isoforms have been reported that are producedby alternative splicing. The TSLP-R is expressed preferentially in myeloid cells includingdendritic cells and activated monocytes, and is weakly expressed in T cells. Expression hasalso been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to theheterodimeric functional receptor (TSLP-R and IL-7R) activates JAK2, STAT3 and STAT5 tostimulate cell proliferation. Ligand receptor interactions haves been implicated in thedevelopment of the hematopoietic system, dendritic cell maturation, and the maintenance andpolarization of human Th2 memory T cells in allergic diseases.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Human TSLP-R:Fc protein
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography, and conjugated with PE under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentrationand Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
Description ：TSLP-R, also known as thymic stromal lymphopoietin protein receptor, cytokine receptor-like 2,CRL2, and IL-XR, is a type I membrane receptor that forms a functional heterodimeric complexwith IL-7R to bind TSLP. The TSLP-R contains a WSXWS motif required for proper proteinfolding and a box1 motif important for association with the JAKs. TSLP-R has a predictedmolecular weight approximately 40 kD, and two isoforms have been reported that are producedby alternative splicing. The TSLP-R is expressed preferentially in myeloid cells includingdendritic cells and activated monocytes, and is weakly expressed in T cells. Expression hasalso been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to theheterodimeric functional receptor (TSLP-R and IL-7R) activates JAK2, STAT3 and STAT5 tostimulate cell proliferation. Ligand receptor interactions haves been implicated in thedevelopment of the hematopoietic system, dendritic cell maturation, and the maintenance andpolarization of human Th2 memory T cells in allergic diseases.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Human TSLP-R:Fc protein
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography, and conjugated with PE under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentrationand Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Bouchlaka MN, et al. 2013. J Exp Med. 210:2223. PubMed
Product Citations：
1. Nováková M, et al. 2020. Haematologica. . PubMed
2. Bouchlaka M, et al. 2013. J Exp Med. 210:2223. PubMed
1. Bouchlaka MN, et al. 2013. J Exp Med. 210:2223. PubMed
Product Citations：
1. Nováková M, et al. 2020. Haematologica. . PubMed
2. Bouchlaka M, et al. 2013. J Exp Med. 210:2223. PubMed
文献支持
抗人TSLPR (TSLP-R) 荧光标记PE 抗体
￥5000
