Description :Ikaros, also known as IKZF1, belongs to a family of zinc-finger DNA-binding proteins thatregulate lymphocyte differentiation. It has the ability to form homo- and heterodimers with othermembers of the Ikaros family, which include Aiolos and Helios. Ikaros can be found on amajority of fetal and adult hematopoietic cell types such as T- and B-cells, natural killer cells(NKs), monocytes/macrophages, and dendritic cells. Ikaros is a tumor suppressor and itsabsence or reduced expression has been reported in several leukemias.
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 underoptimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :ICFC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by intracellular flow cytometry using our TruePhos™ Perm Buffer in Whole Blood Protocol. For flow cytometric staining, the suggested use ofthis reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.