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- 齐源
- 647503
- 国产/进口
- 2025年07月08日
- ICFC
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- 人
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
XBP-1s
- 级别：
XBP-1s Antibody
- 目录编号：
XBP-1s Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
XBP-1s Antibody
- 抗体英文名：
anti-XBP-1s Antibody-PE
- 抗体名：
XBP-1s Antibody
- 标记物：
PE
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
XBP-1s Antibody
- 亚型：
XBP-1s Antibody
- 形态：
XBP-1s Antibody
- 应用范围：
ICFC
- 保存条件：
2-8℃
- 浓度：
XBP-1s Antibody
- 规格：
25 tests/100 tests
| 规格： | 25 tests | 产品价格： | ￥2500.0 |
|---|---|---|---|
| 规格： | 100 tests | 产品价格： | ￥6100.0 |
anti-XBP-1s Antibody-PE详细如下：
Description ：XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of itsability to bind X-box, a conserved transcriptional element in the promoter of human HLA DRgene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is alsoessential for differentiation of plasma cells. XBP-1 upregulates as part of the ER stressresponse, also known as the unfolded protein response. Unspliced XBP-1 is 261 amino acidsand migrates on the SDS-PAGE around 33 kD; spliced XBP-1, recognized by clone 143F,is 371 amino acids and migrates around 55 kD.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：XBP-1s recombinant protein
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with PE under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
Description ：XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of itsability to bind X-box, a conserved transcriptional element in the promoter of human HLA DRgene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is alsoessential for differentiation of plasma cells. XBP-1 upregulates as part of the ER stressresponse, also known as the unfolded protein response. Unspliced XBP-1 is 261 amino acidsand migrates on the SDS-PAGE around 33 kD; spliced XBP-1, recognized by clone 143F,is 371 amino acids and migrates around 55 kD.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：XBP-1s recombinant protein
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with PE under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Tsang KY, et al. 2007. PLOS Biol. 5:568. (IHC) PubMed
2. Farhan H, et al. 2008. EMBO J. 27:2043 (WB) PubMed
3. Farhan H, et al. 2010. J. Cell Biol. 189:997. PubMed
4. Feng-Jin G, et al. 2010. Cell Signal. [Epub ahead of print]
5. Wang L, et al. 2011. Hum Mol Genet. PubMed
6. Li J, et al. 2011. J. Biol Chem. 286:4912. PubMed
7. Wang L, et al. 2011. Hum Mol Genet. 20:1008. PubMed
8. Liu Y, et al. 2011. J Biol Chem. 286:13161. PubMed
9. Shirley CM, et al. 2011 Blood. 117:6297. PubMed
10. Vidal RL., et al. 2012. Hum Mol Genet. PubMed
11. Byrd AE, et al. 2012. J Cell Biol. 196:689. PubMed
12. Dickie LJ, et al. 2012. Ann rheum Dis. 71:2035. PubMed
13. Bonetti P, et al. 2013. Blood. 122:2233. PubMed
14. Maestre L, et al. 2009. Haematologica. 94:419. (IF, IHC)
15. Rodriguez M, et al. 2014. J Biol Chem. 289:22942. PubMed
Product Citations：
1. Grayson KA, et al. 2021. Mol Cancer Ther. 20:833. PubMed
1. Tsang KY, et al. 2007. PLOS Biol. 5:568. (IHC) PubMed
2. Farhan H, et al. 2008. EMBO J. 27:2043 (WB) PubMed
3. Farhan H, et al. 2010. J. Cell Biol. 189:997. PubMed
4. Feng-Jin G, et al. 2010. Cell Signal. [Epub ahead of print]
5. Wang L, et al. 2011. Hum Mol Genet. PubMed
6. Li J, et al. 2011. J. Biol Chem. 286:4912. PubMed
7. Wang L, et al. 2011. Hum Mol Genet. 20:1008. PubMed
8. Liu Y, et al. 2011. J Biol Chem. 286:13161. PubMed
9. Shirley CM, et al. 2011 Blood. 117:6297. PubMed
10. Vidal RL., et al. 2012. Hum Mol Genet. PubMed
11. Byrd AE, et al. 2012. J Cell Biol. 196:689. PubMed
12. Dickie LJ, et al. 2012. Ann rheum Dis. 71:2035. PubMed
13. Bonetti P, et al. 2013. Blood. 122:2233. PubMed
14. Maestre L, et al. 2009. Haematologica. 94:419. (IF, IHC)
15. Rodriguez M, et al. 2014. J Biol Chem. 289:22942. PubMed
Product Citations：
1. Grayson KA, et al. 2021. Mol Cancer Ther. 20:833. PubMed
文献支持
抗 XBP-1s 荧光标记PE 抗体
￥2500 - 6100
