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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
IL-16
- 级别：
IL-16 Antibody
- 目录编号：
IL-16 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
IL-16 Antibody
- 抗体英文名：
anti-human IL-16 Antibody-PE
- 抗体名：
IL-16 Antibody
- 标记物：
PE
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
IL-16 Antibody
- 亚型：
IL-16 Antibody
- 形态：
IL-16 Antibody
- 应用范围：
ICFC
- 保存条件：
2-8℃
- 浓度：
IL-16 Antibody
- 规格：
100 tests
anti-human IL-16 Antibody-PE详细如下：
Description ：Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (proIL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but itsbiologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4 T cells,monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, andalso inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminalrepeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelialcells, and fibroblasts. CD4 and CD9 are the receptors of IL-16.
Verified Reactivity ：Human
Reported Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Peptide corresponding to amino acids 615 to 630 (RRKSLQSKETTAAGDS) of IL-16
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with PE under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
Description ：Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (proIL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but itsbiologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4 T cells,monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, andalso inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminalrepeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelialcells, and fibroblasts. CD4 and CD9 are the receptors of IL-16.
Verified Reactivity ：Human
Reported Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Peptide corresponding to amino acids 615 to 630 (RRKSLQSKETTAAGDS) of IL-16
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with PE under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Cruikshank WW, et al. 1994. P. Natl Acad Sci USA 91:5109. (ICFC)
2. Keane J, et al. 1998. J. Immunol. 160:5945. (Block, ELISA)
3. Chupp GL, et al. 1998. J. Immunol. 161:3114. (Block, IHC)
4. Stoitzner P, et al. 2001. J. Invest. Dermatol. 116:641. (ICFC)
5. Ren F, et al. 2005. J. Immunol. 174:2738. (ICFC)
Product Citations：
1. Noman M, et al. 2015. Cancer Res . 75: 3771-3787. PubMed
1. Cruikshank WW, et al. 1994. P. Natl Acad Sci USA 91:5109. (ICFC)
2. Keane J, et al. 1998. J. Immunol. 160:5945. (Block, ELISA)
3. Chupp GL, et al. 1998. J. Immunol. 161:3114. (Block, IHC)
4. Stoitzner P, et al. 2001. J. Invest. Dermatol. 116:641. (ICFC)
5. Ren F, et al. 2005. J. Immunol. 174:2738. (ICFC)
Product Citations：
1. Noman M, et al. 2015. Cancer Res . 75: 3771-3787. PubMed
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抗人 IL-16 荧光标记PE 抗体
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