- ￥4500
- 齐源
- 657602
- 国产/进口
- 2025年07月10日
- WB, ICC, IP
- 小鼠
- 人、小鼠
6 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
IRF1
- 级别：
IRF1 Antibody
- 目录编号：
IRF1 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
IRF1 Antibody
- 抗体英文名：
Purified anti-IRF1 Antibody
- 抗体名：
IRF1 Antibody
- 标记物：
IRF1 Antibody
- 宿主：
小鼠
- 适应物种：
人、小鼠
- 免疫原：
IRF1 Antibody
- 亚型：
IRF1 Antibody
- 形态：
IRF1 Antibody
- 应用范围：
WB, ICC, IP
- 保存条件：
2-8℃
- 浓度：
0.5 mg/mL
- 规格：
100 µg
Purified anti-IRF1 Antibody详细如下：
Description ：IRF1 is the first identified member of the interferon regulatory transcription factor family. Itsexpression is induced in response to pathogen infection or the stimulation of several cytokines,including type I and II IFN, IL-1, IL-6, and TNF-α. Upon stimulation, IRF1 is transcriptionallyactivated by STAT1 and NFκB transcription factors via the GAS (interferon-gamma-activatedsequence) element in the IRF1 promoter. IRF1 plays important roles in mediating immuneresponse during infection and development of T cells and NK cells. In addition to theimmunomodulatory functions, IRF1 has also shown to be involved in the regulation of cell cycleprogression, tumor suppression, and apoptosis. IRF1-mediated transcription can be repressedby IRF2 through competing for the same binding region on the promoters.
Verified Reactivity ：Human, Mouse
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial human IRF1 recombinant protein (147-325 a.a.)
Formulation ：This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation ：Affinity purified.
Concentration ：0.5 mg/mL
Storage & Handling ：Upon receipt, store undiluted at 4°C.
Application ：WB - Quality tested、ICC, IP - Verified
Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested use of this reagent is 0.5 - 2.0 µg per mL. For immunoprecipitation, the suggested useof this reagent is 2.0 - 10 μg per mL. It is recommended that the reagent be titrated for optimalperformance for each application.
Description ：IRF1 is the first identified member of the interferon regulatory transcription factor family. Itsexpression is induced in response to pathogen infection or the stimulation of several cytokines,including type I and II IFN, IL-1, IL-6, and TNF-α. Upon stimulation, IRF1 is transcriptionallyactivated by STAT1 and NFκB transcription factors via the GAS (interferon-gamma-activatedsequence) element in the IRF1 promoter. IRF1 plays important roles in mediating immuneresponse during infection and development of T cells and NK cells. In addition to theimmunomodulatory functions, IRF1 has also shown to be involved in the regulation of cell cycleprogression, tumor suppression, and apoptosis. IRF1-mediated transcription can be repressedby IRF2 through competing for the same binding region on the promoters.
Verified Reactivity ：Human, Mouse
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial human IRF1 recombinant protein (147-325 a.a.)
Formulation ：This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation ：Affinity purified.
Concentration ：0.5 mg/mL
Storage & Handling ：Upon receipt, store undiluted at 4°C.
Application ：WB - Quality tested、ICC, IP - Verified
Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested use of this reagent is 0.5 - 2.0 µg per mL. For immunoprecipitation, the suggested useof this reagent is 2.0 - 10 μg per mL. It is recommended that the reagent be titrated for optimalperformance for each application.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Product Citations：
1. Velásquez LN, et al. 2017. J Leukoc Biol. 101:759. PubMed
2. Bailey KA, et al. 2019. FASEB J. 33:12888. PubMed
1. Velásquez LN, et al. 2017. J Leukoc Biol. 101:759. PubMed
2. Bailey KA, et al. 2019. FASEB J. 33:12888. PubMed
文献支持
Purified 抗 IRF1 抗体
￥4500
