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- 齐源
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- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
IRF7
- 级别：
IRF7 Antibody
- 目录编号：
IRF7 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
IRF7 Antibody
- 抗体英文名：
Alexa Fluor® 488 anti-IRF7 Antibody
- 抗体名：
IRF7 Antibody
- 标记物：
IRF7 Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
IRF7 Antibody
- 亚型：
IRF7 Antibody
- 形态：
IRF7 Antibody
- 应用范围：
ICFC
- 保存条件：
2-8℃
- 浓度：
IRF7 Antibody
- 规格：
25 tests/100 tests
| 规格： | 25 tests | 产品价格： | ￥2900.0 |
|---|---|---|---|
| 规格： | 100 tests | 产品价格： | ￥6900.0 |
Alexa Fluor® 488 anti-IRF7 Antibody详细如下：
Description ：IRF-7 is a member of the interferon regulatory transcription factor family that plays keyregulatory roles in innate immunity. Upon virus infection, IRF-7 forms a complex with MyD88and TRAF6 when stimulated by toll-like receptors TLR7, TLR8, and TLR9, which in turn resultsin nuclear translocation and induction of interferon gene expression. IRF-7 gene expression isupregulated by the stimulation of interferon through the Jak-STAT signaling pathway, whichforms a positive feedback loop. The protein level of IRF-7 after activation is thendownregulated by the ubiquitin-proteasome system to avoid excessive production ofinterferons that may cause damage to the host. Virus induced type I interferon expression wascompletely abrogated in IRF-7 knockout mice, suggesting that IRF-7 is critical for interferonmediated host defense during virus infection.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial IRF7 recombinant protein (127-503 a.a.)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Excitation Laser ：Blue Laser (488 nm)
Description ：IRF-7 is a member of the interferon regulatory transcription factor family that plays keyregulatory roles in innate immunity. Upon virus infection, IRF-7 forms a complex with MyD88and TRAF6 when stimulated by toll-like receptors TLR7, TLR8, and TLR9, which in turn resultsin nuclear translocation and induction of interferon gene expression. IRF-7 gene expression isupregulated by the stimulation of interferon through the Jak-STAT signaling pathway, whichforms a positive feedback loop. The protein level of IRF-7 after activation is thendownregulated by the ubiquitin-proteasome system to avoid excessive production ofinterferons that may cause damage to the host. Virus induced type I interferon expression wascompletely abrogated in IRF-7 knockout mice, suggesting that IRF-7 is critical for interferonmediated host defense during virus infection.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial IRF7 recombinant protein (127-503 a.a.)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Excitation Laser ：Blue Laser (488 nm)
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文献和实验该产品被引用文献
Product Citations：
1. He J, et al. 2020. Cell Reports. 29(9):2718-2730.e6.. PubMed
1. He J, et al. 2020. Cell Reports. 29(9):2718-2730.e6.. PubMed
文献支持
Alexa Fluor® 488 抗 IRF7 抗体
￥2900 - 6900
