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- 齐源
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- 国产/进口
- 2025年07月13日
- FC, IP
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- 小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD317
- 级别：
CD317 (BST2, PDCA-1) Antibody
- 目录编号：
CD317 (BST2, PDCA-1) Antibody
- 克隆性：
单克隆
- 抗原来源：
大鼠
- 保质期：
CD317 (BST2, PDCA-1) Antibody
- 抗体英文名：
Purified anti-mouse CD317 (BST2, PDCA-1) Antibody
- 抗体名：
CD317 (BST2, PDCA-1) Antibody
- 标记物：
CD317 (BST2, PDCA-1) Antibody
- 宿主：
大鼠
- 适应物种：
小鼠
- 免疫原：
CD317 (BST2, PDCA-1) Antibody
- 亚型：
CD317 (BST2, PDCA-1) Antibody
- 形态：
CD317 (BST2, PDCA-1) Antibody
- 应用范围：
FC, IP
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
100 µg
Purified anti-mouse CD317 (BST2, PDCA-1) Antibody详细如下：
Description ：CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1,is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantlyexpressed on Type I IFN-producing cells (IPCs) in naïve mice, but is up-regulated on most celltypes following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminallydifferentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiplemyeloma, renal cell carcinoma, and melanoma cells. BST2 is a recently identified as IFNinduced cellular response factor that blocks release of HIV-1 and other retroviruses frominfected cells. BST2 has been found to be the natural ligand of ILT7 in human model.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：Mouse plasmacytoid dendritic cells (DCs)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：FC - Quality tested、IP - Reported in the literature, not verified in house
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10 cells in100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Description ：CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1,is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantlyexpressed on Type I IFN-producing cells (IPCs) in naïve mice, but is up-regulated on most celltypes following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminallydifferentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiplemyeloma, renal cell carcinoma, and melanoma cells. BST2 is a recently identified as IFNinduced cellular response factor that blocks release of HIV-1 and other retroviruses frominfected cells. BST2 has been found to be the natural ligand of ILT7 in human model.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：Mouse plasmacytoid dendritic cells (DCs)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：FC - Quality tested、IP - Reported in the literature, not verified in house
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10 cells in100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Blasius AL, et al. 2006. J. Immunol. 177:3260
2. Cocka LJ, et al. 2012. PLoS Pathog. 8:e1002931. PubMed.
Product Citations：
1. Cocka L, Bates P 2012. PLoS One. 8:e1002931. PubMed
2. Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed
3. Prabakaran T, et al. 2021. EBioMedicine. 66:103314. PubMed
4. Olety B, et al. 2021. Sci Adv. 7:eabj7398. PubMed
1. Blasius AL, et al. 2006. J. Immunol. 177:3260
2. Cocka LJ, et al. 2012. PLoS Pathog. 8:e1002931. PubMed.
Product Citations：
1. Cocka L, Bates P 2012. PLoS One. 8:e1002931. PubMed
2. Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed
3. Prabakaran T, et al. 2021. EBioMedicine. 66:103314. PubMed
4. Olety B, et al. 2021. Sci Adv. 7:eabj7398. PubMed
文献支持
Purified 抗小鼠 CD317 (BST2, PDCA-1) 抗体
￥2500
