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- Sigma-Aldrich
- S2130-100G
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- 2026年02月01日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
有现货
- 英文名：
5-Sulfosalicylic acid dihydrate
- CAS号：
5965-83-3
- 保质期：
根据瓶身LOT号查询
- 供应商：
浙江羽翔生物科技有限公司
- 保存条件：
常温
- 规格：
100G
属性
质量水平
200
产品线
ReagentPlus®
检测方案
≥99%
mp
105-110 °C (lit.)
溶解性
water: soluble 100 mg/mL, clear, colorless
SMILES字符串
[H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O
InChI
1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2
InChI key
BHDKTFQBRFWJKR-UHFFFAOYSA-N
一般描述
应用
- Efficient transfer hydrogenation of biomass-derived furfural to furfuryl alcohol over mesoporous Zr-containing hybrids: This research uses 5-sulfosalicylic acid as a ligand to enhance catalytic efficiency, demonstrating potential applications in biofuel production
- Synthesis of polyaniline/5-sulfosalicylic acid composite and its electrochemical properties: Investigates the synthesis of a composite material that exhibits promising electrochemical properties, useful for developing advanced electronic materials
- Controllable 5-sulfosalicylic acid assisted solvothermal synthesis of monodispersed superparamagnetic Fe3O4 nanoclusters: Highlights the role of 5-sulfosalicylic acid in controlling the size and dispersion of magnetic nanoparticles, crucial for various technological applications
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文献和实验In vitro protective effects of plants frequently used traditionally in cancer prevention in Thai traditional medicine: An ethnopharmacological study.
Thai traditional medicine (TTM) has been used widely in cancer management in Thailand. Although several Thai medicinal plants were screened for pharmacological activities related to cancer treatment, such evidence still suffers from the lack of linking with TTM knowledge. To document knowledge and species used in cancer prevention in TTM and to preliminary investigate pharmacological activities related to the documented knowledge of twenty-six herbal drugs used in cancer/mareng prevention. Fieldwork gathering data on TTM concept and herbal medicines used in cancer prevention was performed with TTM practitioners across Thailand. Later, water and ethanol extracts from twenty-six herbal drugs mentioned as being used in cancer prevention were screened for their protective effect against tert-butyl hydroperoxide-induced cell death in HepG2 cells. Then active extracts were investigated for their effects on NQO1 activity, glutathione level, and safety in normal rat hepatocytes. The fieldwork helped in the development of TTM cancer prevention strategy and possible experimental models to test the pharmacological activities of selected medicinal plants. Fifteen plant extracts showed significant protective effect by restoring the cell viability to 40-59.3%, which were comparable or better than the positive control EGCG. Among them, ethanol extracts from S. rugata and T. laurifolia showed the most promising chemopreventive properties by significantly increased NQO1 activity, restored GSH level from oxidative damage, as well as showed non-toxic effect in normal rat hepatocytes. TTM knowledge in cancer prevention was documented and used in the planning of pharmacological experiment to study herbal medicines, especially in cancer, inflammation, and other chronic diseases. The proposed strategy should be applied to in vivo and clinical studies in order to further confirm the validity of such a strategy. Other traditional medical systems that use integrated approaches could also apply our strategy to develop evidence that supports a more rational uses in traditional medicine.
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