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- 详细信息
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
HDAC7
- 级别:
HDAC7 Antibody
- 目录编号:
HDAC7 Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
HDAC7 Antibody
- 抗体英文名:
Purified anti-HDAC7 Antibody
- 抗体名:
HDAC7 Antibody
- 标记物:
HDAC7 Antibody
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
HDAC7 Antibody
- 亚型:
HDAC7 Antibody
- 形态:
HDAC7 Antibody
- 应用范围:
WB, ChIP
- 保存条件:
2-8℃
- 浓度:
HDAC7 Antibody
- 规格:
100 µg
Purified anti-HDAC7 Antibody详细如下:
Description :Histone deacetylases (HDACs) regulate a variety of biological processes by deacetylatinglysine residues in the N-terminal tails of core histones and non-histone proteins. HDAC7 is aclass IIa histone deacetylase and its enzymatic activity is dependent on the interaction withHDAC3. HDAC7 is highly expressed in CD4 CD8 double-positive thymocytes and has beensuggested to repress the expression of Nur77 through the transcription factor MEF2D. HDAC7is mostly localized to the nucleus and can be sequestrated in the cytoplasm by interacting with14-3-3 protein during T cell receptor activation. The nuclear export of HDAC7 leads to theexpression of Nur77 and apoptosis. HDAC7 has been shown to regulate the maturation ofosteoclast and osteoblast, as well as the development of muscle and blood vessel.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Synthetic HDAC7 peptide conjugated to KLH (1-17 a.a.)
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation :The antibody was purified by affinity chromatography.
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :WB - Quality tested、ChIP - Verified
Description :Histone deacetylases (HDACs) regulate a variety of biological processes by deacetylatinglysine residues in the N-terminal tails of core histones and non-histone proteins. HDAC7 is aclass IIa histone deacetylase and its enzymatic activity is dependent on the interaction withHDAC3. HDAC7 is highly expressed in CD4 CD8 double-positive thymocytes and has beensuggested to repress the expression of Nur77 through the transcription factor MEF2D. HDAC7is mostly localized to the nucleus and can be sequestrated in the cytoplasm by interacting with14-3-3 protein during T cell receptor activation. The nuclear export of HDAC7 leads to theexpression of Nur77 and apoptosis. HDAC7 has been shown to regulate the maturation ofosteoclast and osteoblast, as well as the development of muscle and blood vessel.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Synthetic HDAC7 peptide conjugated to KLH (1-17 a.a.)
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation :The antibody was purified by affinity chromatography.
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :WB - Quality tested、ChIP - Verified
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Purified 抗 HDAC7 抗体
¥5300










