- ￥961 - 1433
- 爱必信(absin)
- 上海
- abs823418
- 2025年07月14日
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- 详细信息
- 技术资料
- 保存条件：
Store at -20° C，1 year
- 保质期：
Store at -20° C，1 year
- 英文名：
Docosahexaenoyl Ethanolamide
- 库存：
现货
- 供应商：
爱必信(上海)生物科技有限公司
- CAS号：
162758-94-3
- 规格：
5mg/10mg
| 规格： | 5mg | 产品价格： | ￥961.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥1433.0 |
| 产品描述 | |
| 描述 | Docosahexaenoyl Ethanolamide (DHEA) is an ethanolamine amide of DHA that has been detected in both retina and brain at concentrations similar to those for arachidonoyl ethanolamide (AEA). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, particularly in the retina and brain. A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets on a DHA-supplemented diet compared to a DHA-free control diet. DHEA binds rat brain CB1 receptor with a Ki of 324 nM, which is about 10-fold higher than the Ki for AEA. DHEA inhibits shaker-related voltage-gated potassium channels in the brain slightly better than AEA, with an IC50 of 1.5 μM. |
| 应用 | An ethanolamine amide of DHA |
| 纯度 | ≥98% |
| 浓度 | 20mg/ml |
| 储存/保存方法 | Store at -20° C，1 year |
| 形态 | Liquid |
| 基本信息 | |
| 别名 | Synaptamide |
| 外观 | A solution in ethanol |
| 沸点 | 78° C |
| 折射率 | n20D 1.52 (Predicted) |
| IC50 | Shaker-related voltage-gated potassium channels: IC50 = 1.5 µM (brain) |
| PK值 | pKa: 15.45 (Predicted), pKb: -0.48 (Predicted) |
| Ki 数据 | CB1: Ki= 324 nM (rat brain) |
| 可溶性/溶解性 | Soluble in ethanol, DMSO (~20 mg/ml), DMF (~20 mg/ml), PBS (pH 7.2) (~0.15 mg/ml), and water (0.15 mg/ml at 25° C). |
| MDL | MFCD12912674 |
| PubChem CID | 5283451 |
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