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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD226
- 级别：
CD226 (DNAM-1) Antibody
- 目录编号：
CD226 (DNAM-1) Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
CD226 (DNAM-1) Antibody
- 抗体英文名：
Purified anti-human CD226 (DNAM-1) Antibody
- 抗体名：
CD226 (DNAM-1) 抗体
- 标记物：
CD226 (DNAM-1) Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
CD226 (DNAM-1) Antibody
- 亚型：
CD226 (DNAM-1) Antibody
- 形态：
CD226 (DNAM-1) Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
100 µg
Purified anti-human CD226 (DNAM-1) Antibody详细如下：
Description ：DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells,monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a memberof the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligandsfor CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), whichare broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physicallyassociated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediatedsignaling.
Verified Reactivity ：Human
Reported Reactivity ：African Green, Baboon, Cynomolgus, Rhesus
Antibody Type ：Monoclonal
Host Species ：Mouse
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/m
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Description ：DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells,monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a memberof the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligandsfor CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), whichare broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physicallyassociated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediatedsignaling.
Verified Reactivity ：Human
Reported Reactivity ：African Green, Baboon, Cynomolgus, Rhesus
Antibody Type ：Monoclonal
Host Species ：Mouse
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/m
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Fuchs A, et al. 2004. J. Immunol. 172:3994
Product Citations：
1. Maas RJ, et al. 2020. Oncoimmunology. 9:1843247. PubMed
2. Sanz–Ortega L, et al. 2019. Front Immunol. 1.85625. PubMed
3. Van der Meer JMR, et al. 2021. Oncoimmunology. 10:1981049. PubMed
4. Sander J et al. 2017. Immunity. 47(6):1051-1066 . PubMed
1. Fuchs A, et al. 2004. J. Immunol. 172:3994
Product Citations：
1. Maas RJ, et al. 2020. Oncoimmunology. 9:1843247. PubMed
2. Sanz–Ortega L, et al. 2019. Front Immunol. 1.85625. PubMed
3. Van der Meer JMR, et al. 2021. Oncoimmunology. 10:1981049. PubMed
4. Sander J et al. 2017. Immunity. 47(6):1051-1066 . PubMed
文献支持
Purified 抗人 CD226 (DNAM-1) 抗体
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