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文献和实验Small-conductance Ca2+ −activated potassium (SK) channels constitute a family of ion channels that are regulated by the cytosolic Ca2+ concentration. Increases in the intracellular Ca2+ concentration ([Ca2+ ]i ) result in opening
Characterization of Potassium Channel Binding
Figure 1.17.1 Displacement of [3 H]P 1075 whole‐cell binding to KATP channels in rat A10 cells using P 1075 and two potassium channel–opener compounds. The data was fitted using GraphPad Prism program. Figure kindly contributed by R. Davis Taber
BK Potassium Channel Mutations Affecting Neuronal Function and Epilepsy
. Recently, the large conductance voltage and calcium-activated potassium channel (BK channel) gene and their accessory subunits have been appended to the list of mutations causing epilepsy in humans and mice. BK channels have the specialized role
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