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文献和实验Assembly of Matched Alpha/Beta Subunits to HLA Class II Peptide Receptors
Human antigen presenting cells express three human leukocyte antigen (HLA) class II isotypes (DR, DP, and DQ), which are composed of polymorphic α and β subunits. The combination of polymorphic α- and β-chains results in cis (encoded
PCR-Sequence-Specific Primer Typing of HLA Class I and Class II Alleles
The use of molecular typing methods for defining human leukocyte antigen (HLA) Class I and Class II alleles is now commonplace. Molecular methods offer a greater accuracy than traditional serological methods (1 –5 ) which is reflected
The genes of the human leukocyte antigen (HLA) region control a variety of functions involved in the immune response and influence susceptibility to over 40 diseases. The region maps to the short arm of chromosome 6 and is divided
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