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文献和实验ChIP‐chip for Genome‐Wide Analysis of Protein Binding in Mammalian Cells
chromatin immunoprecipitation (ChIP) with microarrays (chip) to determine protein?DNA interactions occurring in living cells. The high throughput nature of this method makes it an ideal approach for identifying transcription factor targets or chromatin
Site-directed hydroxy radical mapping of nucleosome positions in vitro
assays based on the fact that DNA assembled within a nucleosome is more resistant to cleavage than free DNA. In ideal cases with strongly positioned nucleosomes these methods can yield high resolution mapping of nucleosome positions. However, nucleosomal
Specificity Profiling of Protein‐Binding Domains Using One‐Bead‐One‐Compound Peptide Libraries
., Koesling, D., and Schneider‐Mergener, J. 1999. Interaction of a PDZ protein domain with a synthetic library of all human protein C termini. Angew. Chem. Int. Ed. 38:2000‐2004.
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