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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
Bcl-2
- 级别:
anti-Bcl-2 Antibody
- 目录编号:
anti-Bcl-2 Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
anti-Bcl-2 Antibody
- 抗体英文名:
Alexa Fluor® 488 anti-Bcl-2 Antibody
- 抗体名:
Bcl-2 抗体
- 标记物:
anti-Bcl-2 Antibody
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
anti-Bcl-2 Antibody
- 亚型:
anti-Bcl-2 Antibody
- 形态:
anti-Bcl-2 Antibody
- 应用范围:
ICFC
- 保存条件:
2-8℃
- 浓度:
anti-Bcl-2 Antibody
- 规格:
25 tests/100 tests
| 规格: | 25 tests | 产品价格: | ¥2700.0 |
|---|---|---|---|
| 规格: | 100 tests | 产品价格: | ¥6300.0 |
Alexa Fluor® 488 抗 Bcl-2 抗体详细如下:
Description :Bcl-2 is a conserved anti-apoptotic protein that plays important roles in normal immunity. Itforms homodimers or heterodimers with other Bcl-2 family members. This protein regulatesapoptosis through controlling mitochondrial fusion and fission. Phosphorylation of Bcl-2 hasbeen shown to enhance activity to allow response to extracellular growth-factor-mediatedsignals. Bcl-2 is also regulated by IRES, miR-15a, miR-16-1 and RNA-BP nucleolin.Chromosome 18q21.3 translocation and overexpression of Bcl-2 is frequently observed infollicular lymphomas and some diffuse large B-cell lymphomas.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Synthetic peptide of amino acids 41-54 of human bcl-2 oncoprotein
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488under optimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :ICFC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
Excitation Laser :Blue Laser (488 nm)
Description :Bcl-2 is a conserved anti-apoptotic protein that plays important roles in normal immunity. Itforms homodimers or heterodimers with other Bcl-2 family members. This protein regulatesapoptosis through controlling mitochondrial fusion and fission. Phosphorylation of Bcl-2 hasbeen shown to enhance activity to allow response to extracellular growth-factor-mediatedsignals. Bcl-2 is also regulated by IRES, miR-15a, miR-16-1 and RNA-BP nucleolin.Chromosome 18q21.3 translocation and overexpression of Bcl-2 is frequently observed infollicular lymphomas and some diffuse large B-cell lymphomas.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Synthetic peptide of amino acids 41-54 of human bcl-2 oncoprotein
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488under optimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :ICFC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
Excitation Laser :Blue Laser (488 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Pezzella F, et al. 1993. New Eng. J. Med. 329:690. (IHC)
2. Pezzella F, et al. 1990. Am. J. Pathol. 137:225. (IHC)
3. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
4. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations:
1. Ramos CV, et al. 2020. Cell Reports. 32(3):107910. PubMed
2. Nel I, et al. 2021. Diabetologia. 64(10):2306-2321. PubMed
1. Pezzella F, et al. 1993. New Eng. J. Med. 329:690. (IHC)
2. Pezzella F, et al. 1990. Am. J. Pathol. 137:225. (IHC)
3. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
4. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations:
1. Ramos CV, et al. 2020. Cell Reports. 32(3):107910. PubMed
2. Nel I, et al. 2021. Diabetologia. 64(10):2306-2321. PubMed
文献支持
Alexa Fluor® 488 抗 Bcl-2 荧光抗体
¥2700 - 6300










