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Anti-CD19-Anti-CD3 Bispecific

Molecule
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  • 询价
  • BPS Bioscience已认证
  • 美国
  • 100441-1
  • 2025年11月26日
    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 保存条件

      -80°C (dry ice)

    • 保质期

      Stable for at least 12 months at -80°C. Avoid freeze/thaw cycles.

    • 英文名

      Anti-CD19-Anti-CD3 Bispecific Molecule

    • 库存

      1

    • 供应商

      BPS Bioscience Inc.

    • CAS号

      /

    • 规格

      50 µg

    Anti-CD19-Anti-CD3-His-Tag is a purified recombinant human bispecific T cell Engager (BiTE) based on Amgen's Blinatumomab. This BiTE has been tested for specific activity in both ELISA binding assay to CD19-biotin and functional reporter assays using Jurkat/NFAT-luc or Jurkat/IL2-Luc reporter cell lines in the presence of CD19+ Raji cells.

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    • 作者
    • 内容
    • 询问日期
    图标文献和实验
    该产品被引用文献
    This product is for research use only. It is not suitable for human diagnostic or therapeutic use. The anti-CD19-Anti-CD3-His-Tag can be used as a reference BiTE for studying CD19+ cancer cell-mediated T cell activation, using either primary T cells or reporter cell lines such as Jurkat/NFAT-luc (BPS #60621) or Jurkat/IL2-luc (BPS #60481).
    相关实验
    • How to Make Bispecific Antibodies

      of two molecules of Fab’-A(mal) with two free SH-groups at the hinge of a single Fab’-B molecule (see Note 3 ). The remaining free SH groups on Fab’-B are alkylated, and the F(ab’)2 bispecific antibody product (Fab’-A x Fab’-B) is separated by gel filtration

    • Intracellular Targeting Using Bispecific Antibodies

      The technological development and application of bispecific antibodies for biological research have advanced steadily since the idea of creating hybrid reagents with dual specificity was first promulgated by Nisonoff and Rivers

    • Production of Bispecific Antibodies: Diabodies and Tandem scFv

      Recombinant bispecific antibodies have many different applications; especially promising is their therapeutic potential due to their ability to retarget an effector molecule or a cell to a disease-related target structure. In the last years

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