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Anticancer agent 144
CAS No. : 2948340-59-6
MCE 国际站：Anticancer agent 144
产品活性：Anticancer agent 144 (化合物444) 是一种 PTPN2/PTP1B 双重抑制剂，其 IC50 值均 ＜2.5 nM。Anticancer agent 144 可用于癌症的研究。
研究领域：Metabolic Enzyme/Protease
作用靶点：Phosphatase
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文献和实验Tyrosine Kinase Inhibitors Against EGF Receptor-Positive Malignancies
The role of protein tyrosine kinases (PTKs) in the survival of cancer cells and their potential use in anticancer therapy has led to their selection as anticancer drug targets. Tyrosine kinases which are being studied for this purpose include
Immunosuppressors as Multidrug Resistance Reversal Agents
of anticancer agent-induced apoptosis. In fact, CSA and PSC833 are also able to respectively inhibit ceramide glycosylation and stimulate de novo ceramide synthesis. This could enhance the cellular level of ceramide and potentiate apoptosis induced
99mTc-Annexin A5 Uptake and Imaging to Monitor Chemosensitivity
Most anticancer agents act by inducing apoptosis in sensitive tumor cells. Hence, in many types of cancers, significant increase of tumor apoptosis after chemotherapy correlates with tumor chemosensitivity. Theoretically, a reliable
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