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NF- κB Reporter (Luc) - Raw 26

4.7 Cell line
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  • 询价
  • BPS Bioscience已认证
  • 79978
  • 美国
  • 2025年12月22日
    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      1

    • 供应商

      BPS Bioscience

    • 细胞类型

      稳转细胞系

    • 品系

      Raw 264.7

    • 组织来源

      /

    • 相关疾病

      多种

    • 物种来源

      mouse

    • 免疫类型

      多种

    • 器官来源

    • 运输方式

      干冰

    • 年限

      10

    • 生长状态

      良好

    • 英文名

      NF- κB Reporter (Luc) - Raw 264.7 Cell line

    • 规格

      2管

    The NF-κB reporter (Luc)-Raw 264.7 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

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    图标文献和实验
    该产品被引用文献
    • Screen for activators or inhibitors of NF-κB signaling pathway.
    • Screen for activators or inhibitors of RANKL/RANK pathway.

    相关实验
    • 【讨论】抑制免疫到底是好还是坏?

      cellular responses such as integrin-mediated cell adhesion [21] and phagocytic uptake (Figure 5). Since the activation of PI3K/Akt, but not MAPKs, is necessary for these inflammation-related cellular events as well as for activation of NF-κB [22

    • 细胞信号通路相关文献

      . In this study, we characterized the pharmacological profile of a novel curcumin analog P1 and elucidate the related mechanisms.Methods:HEK293/NF-κB cells, stably transfected with an NF-κB-responsive luciferase reporter plasmid, were generated for high-throughput

    • MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2a

      as independent factors. In Table 1, p values were adjusted by the false discovery rate method (17 ). Treatment effects shown in Table 2b and Fig. 3a were modeled with two coefficients (cell line, treatment) for time point 4 h, p values arise from t statistics

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    NF- κB Reporter (Luc) - Raw 264.7 Cell line
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