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NF- κB Reporter (Luc) - THP-1

Cell Line
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  • 询价
  • BPS Bioscience已认证
  • 79645
  • 美国
  • 2025年12月21日
    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      1

    • 供应商

      BPS Bioscience

    • 细胞类型

      稳转细胞系

    • 品系

      THP-1

    • 组织来源

      /

    • 相关疾病

      多种

    • 物种来源

      human

    • 免疫类型

      多种

    • 器官来源

    • 运输方式

      干冰

    • 年限

      10

    • 生长状态

      良好

    • 英文名

      NF- κB Reporter (Luc) - THP-1 Cell Line

    • 规格

      2管

    The NF-κB reporter (Luc)-THP-1 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

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    图标文献和实验
    该产品被引用文献
    • Monitor NF-κB signaling pathway activity. • Screen for activators or inhibitors of NF-κB signaling pathway.
    相关实验
    • Imaging NF-B Signaling in Mice for Screening Anticancer Drugs

      . Currently, there are various assays available to study NF-κB activation in vitro, however, techniques involving the imaging of NF-κB in vivo models remains limited. Male NF-κB-RE-luc (Oslo) mice from Xenogen Corporation (Alameda, California) provide a great model for studying

    • Cell-Based Reporter Assay to Analyze Activation of Nod1 and Nod2

      pathways. In this chapter, we describe a quick and reliable cell-based assay using a luciferase reporter to measure Nod1- and Nod2-mediated NF-κB activation. The described protocol was successfully applied to analyze the influences of overexpressed proteins

    • How to Monitor NF-B Activation After Photodynamic Therapy

      The nuclear factor-kappa B (NF-κB) is a multipotent factor involved in many cellular processes such as inflammation, immune response and embryonic development and it can be activated by a large number of stimuli. Consequently

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    NF- κB Reporter (Luc) - THP-1 Cell Line
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